7 min read
Fecal Zonulin - What does it tell us?
What is Zonulin?
Zonulin, used in conjunction with other fecal inflammation markers such as calprotectin, can help...
Accurately identifying IgE-mediated allergies is critical, with reactions ranging in severity from mild to life-threatening.
IgE is a true allergy; when IgE is released, there is an immediate (seconds to hours) reaction. IgE reactivity can persist for years or a lifetime due to the presence of B-memory cells in the bone marrow, even if the food has been avoided. Food allergies are recognized to trigger adverse reactions such as skin conditions, GI problems, anaphylaxis, and more. With proper identification and elimination of the offending foods, many experience symptom relief, and reaction evasion.
When testing for food allergies, US BioTek uses two main categories, Food Allergies, and Aeroallergens. Testing and measuring for both gives us a clear picture of not only which foods cause a reaction but what two allergens together are causing cross-reactivity.
Pollens and spores from trees, grasses, mold, dust, and others can produce symptoms that range from minor to severe in affected individuals. Our inhalant panels assess IgG, IgG4, and IgA antibody response to 48 common allergens, and IgE response to 140 allergens, providing helpful information for effective allergy management. A 15-Mold panel for IgE testing is also offered.
Up to 60 percent of all food reactions occur because of cross-reactions between food and pollen.
Pollen exposures can promote cross-reactions with commonly eaten foods because there are common proteins found in the pollens that are shared with other types of fruit and vegetable plants. These cross-reactions can exacerbate food sensitivity reactions during the pollen season.
Food and cuisine create a beautiful foundation for cultures around the world. Depending on regionality, ethnicity, personal preferences, and more, the foods that make up an individual's diet can vary greatly. To ensure our practitioners have access to food allergy panels that fit the diets of their patients and address as many relevant antigens as possible, US BioTek has developed twelve unique allergy panels.
Our IgE panels utilize a quantitative ELISA (enzyme linked immunosorbant assay) analysis of the specific immunoglobin IgE identified for the chosen diet panels’ food and spice analytes.
We follow a meticulous process to extract the critical component from each analyte (food and inhalant trigger) to ensure the antibody present in the patients’ sample will bind properly and validate results with positive and negative controls. Once attached to the antigens, antibodies are detected through spectrophotometric analysis, where the values are directly proportional to the concentration of the analytes in the sample. For additional accuracy, we perform duplicate testing to ensure there are no discrepancies.
The dried blood spot collection method utilizes a simple finger prick and collection card. This method is ideal drop shipping to telehealth patients and clinics without venipuncture capabilities.
The serum collection method requires a modest blood draw.
The Microtainer method requires collection of 600 mcl of blood
Apr 23, 2024by Dr. Andrea Gruszecki, ND
Zonulin, used in conjunction with other fecal inflammation markers such as calprotectin, can help...
Mar 13, 2024by Dr. Andrea Gruszecki, ND
Why do some children have problems with IgE allergy as infants? A history of IgE-mediated allergic disorders in infancy...
Jan 24, 2024by US BioTek Marketing Department
There are many ways a body can demonstrate an aversion to specific foods, with allergies, sensitivities and...
US BioTek offers a 44 IgE Food Panel and 36 IgE Inhalant panel that can be run with a dried blood spot test. This means you aren't required to go to a phlebotomist to take this test—just a finger prick on a piece of paper provided by one of our test kits.
For our other tests, you can go to any phlebotomist to have them collect a serum sample using the vials in our test kits.
Visit our Blood Draw Locations Page to find a phlebotomist near you.
In general, when someone has a food allergy, it is an immediate response to food entering their system with severe symptoms like rash, hives, swelling of the lips, mouth, or throat, and other symptoms commonly associated with what we know as true allergies.
In contrast, IgG reactions are delayed-type hypersensitivity reactions. In other words, the symptoms are often not immediate. Instead, they can appear hours or even days after eating the offending food. These delayed reactions can lead to symptoms such as diarrhea, constipation, abdominal bloating, nasal congestion, chronic sinus infections, joint pain, eczema, and headaches.
The Total IgE test actually comes with the purchase of any test under the "Food Allergy" and "Aeroallergens" categories in our Price List.
Providers can view and download results through our secure Clinician Portal, or request results by email.
Please note that US BioTek does not discuss test results directly with patients. Practitioners assume the responsibility of relaying test results to their patients. All results are confidential.
Test kits are available to registered providers upon request. Use our online submission form to order the collection kits you require.
Easy collection and low volume specimen requirements are advantages of the US BioTek testing methodology. Follow our simple instructions.
Upon completion of specimen collection, complete our test requisition form and include it in your specimen shipment.
Providers can view and download results through our secure Clinician Portal, or request results by email.
Please note that US BioTek does not discuss test results directly with patients. Practitioners assume the responsibility of relaying test results to their patients. All results are confidential.